To produce spider silk protein recombinantly, we selected only a portion of the gene sequence that spiders use to make spidroins. We call this the mini-spidroin. The selected gene sequence was then cloned into E. coli bacteria.
Optimized culture and purification conditions have resulted in a reproducible process. We are now working further on enhancing the quality of the final product and increasing yield.
With several years of designing Spiber™ plus good control of its production, we know how to adjust the Spiber™ format and function for any application in our focus areas: