Why is Spiber unique?
Spiber™ is a biomaterial made of recombinant spider silk protein with a unique set of properties. It combines silk’s inherent material properties, such as high tensile strength and high elasticity, with biomaterial control and technological flexibility stemming from recombinant production.
Spiber™ – for a physical challenge:
Due to its natural properties, Spiber™ is elastic yet mechanically strong, chemically stable yet biodegradable
- As strong as mammalian tendons with a tensile strength of 0.1-0.2 GPa
- Stable up to +267°C
- Chemically stable in buffers and solvents such as 6M Gdn-HCl, 1M NaOH and methanol
Spiber™ – for optimal function:
Spiber™ has a variety of formats and functional properties that fit many applications
- Four Spiber™ formats: fiber, film, foam and mesh
- Several biochemical signaling molecules, e.g. cell adhesion sites and growth factors, have been connected to Spiber™ through genetic modification. Attachment of more complex molecules is under development
Spiber™ – for in-vivo use:
Spiber™ integrates in biological systems with good biocompatibility
- Attached cells grow well and function normally
- By-products from recombinant production, e.g. endotoxins, are efficiently removed
- Subcutaneous implantation in rats shows good biocompatibility